Antenatal Corticosteroids – Is it a Panacea for the Fetus and the Newborn?

Authors

  • P Madhava Chandran Nair KIMS & Ananthapuri, TVM, Kerala, India

DOI:

https://doi.org/10.52314/fnb.2021.v1i1.3

Keywords:

Antenatal Steroids, Fetus & Newborn

Abstract

A single course of corticosteroids for pregnant women between 24 0/7 weeks and 33 6/7 weeks of gestation at risk of preterm delivery within 7 days is the standard antenatal therapy to accelerate fetal lung maturation and prevent respiratory distress syndrome. The benefits include not only a reduction in the risk of RDS (34%) but also a substantial reduction in mortality (32%), Intra-ventricular hemorrhage (IVH) (45%), Necrotizing enterocolitis (NEC) (nearly 50%) and mechanical ventilation need (30%) and systemic infections in the first 48 hours (40%). Extrapolation of this therapy to late preterm and elective Caesarean section for early term deliveries may reduce respiratory distress and transient tachypnea of newborn but may lead to undesirable effects like hypoglycemia, neuro-sensory and behavioral disabilities.

Author Biography

P Madhava Chandran Nair, KIMS & Ananthapuri, TVM, Kerala, India

MD, DCH, DNB, DM (Neonatology)
FIMSA, FRCP, Fellow Neonatology, Sydney, Australia
Prof: & HOD Pediatrics & Neonatology (Rtd.),
Emeritus Prof, SATH, Government Medical College, Trivandrum
Hon: Consultant, KIMS & Ananthapuri, TVM, Kerala, India

Published

2021-05-07

How to Cite

1.
Chandran Nair PM. Antenatal Corticosteroids – Is it a Panacea for the Fetus and the Newborn?. FNB [Internet]. 2021 May 7 [cited 2022 Oct. 3];1(1):6-9. Available from: https://www.fetusandnewborn.com/journal/index.php/fnb/article/view/3