Soft Markers of Down Syndrome

Authors

  • Rinshi Abid Elayedatt Amrita Institute of Medical Sciences & Research Centre, Kochi, Kerala, India.
  • Vivek Krishnan Amrita Institute of Medical Sciences & Research Centre, Kochi, Kerala, India.

DOI:

https://doi.org/10.52314/fnb.2022.v2i1.23

Keywords:

Down Syndrome, Aneuploidy Soft Markers, Screening Trisomy 21

Abstract

Down syndrome is the most common congenital cause for mental disability. It is an aneuploidy that is potentially detectable in the prenatal period by biochemical and ultrasound markers. The ultrasound findings (soft markers) are not structural anomalies per se and are usually clinically insignificant except for their association with aneuploidy. However, these soft markers are particularly important in screening for trisomy 21 fetuses as majority of them will not have any major congenital anomalies detectable on ultrasound.

Author Biographies

Rinshi Abid Elayedatt, Amrita Institute of Medical Sciences & Research Centre, Kochi, Kerala, India.

MS DGO DNB PDF (Fetal Medicine) Assistant Professor, Division of Fetal Medicine & Perinatology, 

Vivek Krishnan, Amrita Institute of Medical Sciences & Research Centre, Kochi, Kerala, India.

 MS DGO DNB MNAMS PDF
(Fetal Medicine) Associate Professor and Head of Department, Division of Fetal Medicine & Perinatology, 

Published

2022-05-23

How to Cite

1.
Abid Elayedatt R, Krishnan V. Soft Markers of Down Syndrome. FNB [Internet]. 2022 May 23 [cited 2022 Oct. 3];2(1):18-20. Available from: https://www.fetusandnewborn.com/journal/index.php/fnb/article/view/23