Comparison of Serum Bilirubin to Transcutaneous Bilirubin During and After Phototherapy

Authors

  • Swetha K Thappa Aster MIMS Hospital, Calicut, Kerala
  • M R Anand Aster MIMS Hospital, Calicut, Kerala
  • Preetha Remesh Aster MIMS Hospital, Calicut, Kerala
  • Vishnu Mohan Aster MIMS Hospital, Calicut, Kerala
  • K R Divia Aster MIMS Hospital, Calicut, Kerala

DOI:

https://doi.org/10.52314/fnb.2021.v1i1.2

Keywords:

Transcutaneous Bilirubin, Photo-Occlusive, Phototherapy

Abstract

Objective: To compare transcutaneous bilirubin with total serum bilirubin in neonates during and after phototherapy
Study design: A prospective observational study for one year
Participants: 799 neonates >35 weeks of gestation, developing jaundice within 10 days of life.
Intervention: A photo-occlusive patch was applied over the sternum. TcB assessment with Drager JM 103 multi wavelength handheld transcutaneous bilirubinometer was done in this area paired with a concurrent serum sample during and 24 hours after stopping phototherapy.
Outcome: In our study the mean TCB during phototherapy was 13.26 ± 2.42 mg/dl with minimum value of 4.50 mg/dL and maximum value of 18.40 mg/dL in the study population (95% CI 13.09 to 13.43 mg/dL). The mean TSB during phototherapy was 13.06 ± 2.52 mg/dl with minimum value of 4.30 mg/dL and maximum value of 18.70 mg/dl in the study population (95% CI 12.88 to 13.23 mg/dL). The mean TCB 24 hours after stopping phototherapy was 10.37 ± 2 mg/dL with minimum value of 4.20 mg/dL and maximum value of 16.10 mg/dL in the study population (95% CI 10.33 to 10.61 mg/dL). The mean TSB 24 hours after stopping phototherapy was 10.47 ± 2.02 mg/dL, minimum value of 4.80 mg/dl and maximum value of 15.30 mg/dL in the study population (95% CI 10.33 to 10.61).
Results: Transcutaneous bilirubin has a good correlation with total serum bilirubin during phototherapy. (r=0.881, P<0.001). Transcutaneous bilirubin has a significant correlation with total serum bilirubin after phototherapy. (r=0.912, P<0.001).
Conclusion: In our study transcutaneous bilirubin correlated significantly with total serum bilirubin at the patched sternal site during and 24 hours after stopping phototherapy, supporting previous studies.

Author Biographies

Swetha K Thappa, Aster MIMS Hospital, Calicut, Kerala

DNB Paediatrics Resident, Department of Paediatrics

M R Anand, Aster MIMS Hospital, Calicut, Kerala

MD, Senior Consultant, Department of Paediatric

Preetha Remesh, Aster MIMS Hospital, Calicut, Kerala

MRCPCH, Senior Consultant, Department of Neonatology

Vishnu Mohan, Aster MIMS Hospital, Calicut, Kerala

FNB, Consultant, Neonatology


K R Divia , Aster MIMS Hospital, Calicut, Kerala

Consultant, Neonatology

Published

2021-05-07

How to Cite

1.
K Thappa S, Anand MR, Remesh P, Mohan V, Divia KR. Comparison of Serum Bilirubin to Transcutaneous Bilirubin During and After Phototherapy. FNB [Internet]. 2021 May 7 [cited 2022 Oct. 3];1(1):2-5. Available from: https://www.fetusandnewborn.com/journal/index.php/fnb/article/view/2

Issue

Section

Original Research